Dr. Syed  Faisal Haider Zaidi
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Dr. Syed Faisal Haider Zaidi

Assistant Professor
King Saud Bin Abdulaziz University of Health Sciences, Saudi Arabia

Highest Degree
Ph.D. in Pharmacology from University of Toyama, Japan

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Dr. Syed Faisal Haider Zaidi is currently working as Assistant Professor in Department of Basic Medical Sciences, College of Medicine, King Saud bin Abulaziz University, Jeddah, Saudi Arab. He obtained his PhD in Pharmacology from University of Toyama, Japan in 2009. His area of interest covers mostly on the pathogenesis of H. pylori associated disorders like peptic ulcer and gastric cancer and various strategies to treat and prevent these disorders. He has keen interest in The role of medicinal plants and spices in gastrointestinal (Gi) disorders not only specific to H. Pylori but also other GI disorders like inflammatory bowel disease, food allergy, and inflammatory bowel syndrome. He has published more than 20 papers with high citations, one international patent. He has been awarded with Young Investigator award in 2013 in Korea. He is member of following scientific societies, American Society of Pharmacology and Experimental Therapeutics, International Society of Ethnopharmacology, USA, Japanese Society for Helicobacter Research, Japan, Pharmaceutical Society of Japan, Japan, Infectious Disease Society of Pakistan, Pakistan Association for Eastern Medicine, and Pakistan Biological Safety Association. He is also serving as reviewer in number of journals and also member of editor board.

Area of Interest:

Pharmacology and Toxicology
Medicinal Plants
Gastrointestinal Disorders
H. Pylori
Inflammatory Bowel Disease

Research Publications in Numbers


Selected Publications

  1. Zaidi, S.F., 2016. Helicobacter pylori associated Asian enigma: Does diet deserve distinction? World J. Gastrointestinal Oncol., 8: 341-350.
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  2. Muhammad, J.S., S.F. Zaidi, Y. Zhou, H. Sakurai and T. Sugiyama, 2016. Novel epidermal growth factor receptor pathway mediates release of human β-defensin 3 from Helicobacter pylori-infected gastric epithelial cells. Pathog. Dis., 10.1093/femspd/ftv128.
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  3. Zaidi, S.F., M. Aziz, J.S. Muhammad and M. Kadowaki, 2015. Diverse pharmacological activities of Cinnamomum cassia: A review. Pak. J. Pharm. Sci., .
  4. Zaidi, S.F., J.S. Muhammad, K. Usmanghani and T. Sugiyama, 2015. Pharmacological ins and outs of medicinal plants against Helicobacter pylori: A review. Pak. J. Pharm. Sci., 28: 1171-1176.
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  5. Zaidi, S.F., A. Refaat, M. Shin, J.S. Muhammad, I. Saiki, T. Sugiyama and H. Sakurai, 2015. Helicobacter pylori induces serine phosphorylation of EGFR via novel TAK1-p38 activation pathway in an HB- EGF-independent manner. Helicobacter, 10.1111/hel.12215.
    CrossRef  |  
  6. Sheikh, Z.A., S. Shakeel, S. Gul, A. Zahoor, S.S. Khan, F.H. Zaidi and K. Usmanghani, 2015. A novel HPTLC method for quantitative estimation of biomarkers in polyherbal formulation. Asian Pac. J. Trop. Biomed., 5: 955-959.
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  7. Sheikh, Z.A., A. Zahoor, S.S. Khan, S. Naveed, S.F. Zaidi and K. Usmanghani, 2015. Ivy Herbal Products for Cough and its Validation for Hederacoside C Biomarker Determination with HPLC _PAD Techniques. J. Pharm. Pharm. Sci., 3: 01-06.
  8. Shakeel, S., K. Usmanghani, S. Gul, Z.A. Sheikh, S.F. Zaidi and M. Lateef, 2015. Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug Entoban. Afr. J. Pharm. Pharmacol., 9: 982-987.
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  9. Rehman, R., S. Jawed, S.F. Zaidi, M. Baig and K. Ahmed, 2015. Role of Interleukin-I β in conception after intracytoplasmic sperm injection. J. Pak. Med. Assoc., 65: 49-53.
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  10. Rehman, M.U., P. Jawaid, Q.L. Zhao, S.F. Zaidi, T.A. Mir, K. Usmanghani and T. Kondo, 2015. Induction of Apoptosis by Selected Pakistani Medicinal Plants in Human Lymphoma U937 Cells. J. Pharm. Pharm. Sci., 3: 19-24.
  11. Qureshi, T., A. Saeed, K. Usmanghani, H.M. Asif and S.F. Zaidi, 2015. ShigelDysent efficacy in alleviating clinical sign and symptoms prevailing in Shigellosis. Int. J. Gastroenterol. Disord. Ther., Vol. 2, 10.15344/2393-8498/2015/114.
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  12. Nawaz, A., S.F. Zaidi, K. Usmanghani and I. Ahmad, 2015. Concise review on the insight of hepatitis C. J. Taibah Univ. Med. Sci., 10: 132-139.
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  13. Muhammad, J.S., S.F. Zaidi, S. Shahryar, A. Refat, K. Usmanghani, I. Saiki and T. Sugiyama, 2015. Anti-inflammatory effect of cinnamaldehyde in Helicobacter pylori induced gastric inflammation. Biol. Pharm. Bull., 38: 109-115.
  14. Muhammad, J.S., S.F. Zaidi and M. Ishaq, 2015. Ins and outs of Helicobacter pylori association with rheumatic diseases. Int. J. Rheumatol. .
  15. Asif, H.M., S.F. Zaidi, T. Sugiyama, N. Akhtar and K. Usmanghani, 2015. Symptomatic improvement and eradication rate by quadruple and phytomedicine-based therapy in Helicobacter pylori infection: A comparative randomized trial. Alter. Ther. Health Med., .
  16. Asif, H.M., S.F. Zaidi, T. Sugiyama, N. Akhtar and K. Usmanghani, 2015. Phytomedicine-based and Quadruple Therapies in Helicobacter pylori Infection: A Comparative, Randomized Trial. Altern. Ther. Health Med., 21: 33-39.
  17. Zaidi, S.F., J.H. Kim, Y. Tomoe, K. Usmanghani and M. Kadowaki, 2014. Effect of Pakistani medicinal plants on IgE/antigen-and ionophore-induced mucosal mast cells degranulation. Pak. J. Pharm. Sci., 27: 1041-1048.
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  18. Zaidi, S.F. and T. Sugiyama, 2014. Antibacterial and anti-inflammatory effects of medicinal plants or spices against Helicobacter pylori: A review. Helicob. Res., 17: 430-436.
  19. Nawaz, A., S. Bano, Z.A. Sheikh, K. Usmanghani, I. Ahmad, S.F. Zaidi, A. Zahoor and I. Ahmad, 2014. Evaluation of acute and repeated dose toxicity of the polyherbal formulation linkus syrup in experimental animals. Chinese Med. Vol. 5 .
  20. Muhammad. J.S., S.F. Zaidi and K. Usmanghani, 2014. Epidemiological and pathophysiological review of Helicobacter pylori. J. Pharm. Pharm. Sci., 2: 45-55.
  21. Hayashi, S., T. Hamada, S.F. Zaidi, M. Oshiro and J. Lee et al., 2014. Nicotine suppresses acute colitis and colonic tumorigenesis associated with chronic colitis in mice. Am. J. Physiol. Gastroin. Liver Physiol., 307: G968-G978.
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  22. Yakoob, J., Z. Abbas, R. Khan, M.W. Usman and S. Hamid et al., 2013. Anti-Helicobacter pylori activity and inhibition of Helicobacter pylori-induced release of IL-8 in AGS cells by plant extracts. J. Med. Plant Res., 7: 970-979.
  23. Muhammad, J.S., T. Sugiyama and S.F. Zaidi, 2013. Gastric pathophysiological ins and outs of helicobacter pylori: A review. J. Pak. Med. Assoc., 63: 1528-1533.
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  24. Ahmed, K. and S.F. Zaidi, 2013. Treating cancer with heat; Hyperthermia as an emerging strategy to enhance apoptosis in cancer cells. J. Pak. Med. Asso., 63: 504-508.
  25. Zaidi, S.F., J.S. Muhammad, S. Shahryar, K. Usmanghani, A.H. Gilani, W. Jafri and T. Sugiyama, 2012. Anti- inflammatory and cytoprotective activity of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells. J. Ethnopharmacol., 141: 403-410.
  26. Zaidi, S.F.H., T. Yamamoto, A. Refaat, K. Ahmed and H. Sakurai et al., 2009. Modulation of activation‐induced cytidine deaminase by curcumin in helicobacter pylori‐infected gastric epithelial cells. Helicobacter, 14: 588-595.
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  27. Zaidi, S.F.H., K. Yamada, M. Kadowaki, K. Usmanghani and T. Sugiyama, 2009. Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori. J. Ethnopharmacol., 121: 286-291.
    CrossRef  |  
  28. Zaidi, S.F.H., K. Ahmed, T. Yamamoto, T. Kondo, K. Usmanghani, M. Kadowaki and T. Sugiyama, 2009. Effect of resveratrol on Helicobacter pylori-induced interleukin-8 secretion, reactive oxygen species generation and morphological changes in human gastric epithelial cells. Biol. Pharm. Bull., 32: 1931-1935.
  29. Zaidi, S.F.H., I. Yoshida, F. Butt, M.A. Yusuf, K. Usmanghani, M. Kadowaki and T. Sugiyama, 2009. Potent bactericidal constituents from Mallotus philippinensis against clarithromycin and metronidazole resistant strains of Japanese and Pakistani Helicobacter pylori. Biol. Pharm. Bull., 32: 631-636.
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  30. Zaidi, S.F., K. Yamada, M. Kadowaki, K. Usmanghani and T. Sugiyama, 2009. Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori. J. Ethnophamacol., 121: 286-291.
    CrossRef  |  PubMed  |  Direct Link  |  
  31. Muhammad, J.S., S.F. Zaidi and T. Sugiyama, 2009. Epidemiological Ins and Outs of Helicobacter pylori : A review. J. Pak. Med. Assoc., 62: 955-959.
  32. Ahmed, K., Y. Matsuya, H. Nemoto, S.F.H. Zaidi and T. Sugiyama et al., 2009. Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain. Chemico-Biol. Int., 177: 218-226.
    CrossRef  |  
  33. Widyawaruyanti, A., S.F.H. Zaidi, S. Awale and S. Kadota, 2007. Traditional medicine of Madura island in Indonesia. J. Trad. Med., 24: 90-103.
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  34. Subehan, S.F.H. Zaidi, S. Kadota and Y. Tezuka, 2007. Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): Identification and characterization of a mechanism-based inactivator. J. Agric. Food Chem., 55: 10162-10167.
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  35. Zaidi, S.F.H., S. Awale, S.K. Kalauni, Y. Tezuka, H. Esumi and S. Kadota, 2006. Diterpenes from Pini Resina and their preferential cytotoxic activity under nutrient-deprived condition. Planta Medica-Nat. Prod. Med. Plant Res., 72: 1231-1234.
  36. Usmanghani, K., A. Ahmad, S.F. Zaidi and H. Nazar, 2006. Diseases pattern at the paediatric OPD of shifaul-mulk memorial hospital Hamdard University, Madinatul Hikmah, Karachi. Hamdard Medicus, 2: 16-22.
  37. Nguyen, M.T., S. Awale, Y. Tezuka, L. Shi and S.F. Zaidi et al., 2005. Hypouricemic effects of acacetin and 4,5-O-Dicaffeoylquinic acid methyl ester on serum uric acid levels in potassium oxonate-pretreated rats. Biol. Pharm. Bull., 28: 2231-2234.
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